S4 (Andarine)

Shortly about Andarine

•  Significantly increases muscle mass, strength performance and burns fat, which together gives athletes a relief and powerful appearance and venousness.  
•  It has significantly less effect on suppressing your own testosterone than most other SARMs, making it a very valuable SARM considering its high potency. 
•  It has an unpleasant, but completely reversible effect, distorting vision during the reception. 
•  has a protective effect on the prostate gland 

What is Andarine

S4 was first developed by GTx. This is a first generation SARM. It was one of the first SARMs to be proven effective, but its clinical trials were not suspended. The reason for this may have been a side effect that it has on vision – an emerging yellowish tint, as well as night blindness. This side effect is experienced by many users, although it disappears shortly after completing to use it.  Since S4 trials are over, it looks like this compound will never be commercialized because there are more effective compounds like LGD4033 or MK-2866. S4 is commonly used for fat loss, in much the same way as MK-2866. Most people rank Andarine in terms of severity of testosterone suppression as the strength of its positive effects somewhere between Ostarine and LGD 4033. S4 is definitely much stronger than Ostarine but weaker than LGD4033. 

Researches  

Andarine was studied in rats for 120 days. This study revealed that S4 has the ability to reduce fracture rates by minimizing falls, increasing muscle strength and directly affecting bones. The study also showed that doses of S4 were effective in increasing skeletal muscle mass and strength gains and reducing body fat. Andarine has also been shown to have a unique potential to prevent bone resorption as well as promote bone anabolism. 

Effects 

•  Increase in muscle mass. S4 allows you to significantly increase muscle mass and give the body a more sculpted look.  
•  Increase in strength indicators. Also, according to reddit users, S4 significantly increases strength. 
•  Decreased body fat. In addition to the fact that under the influence of Andarine muscle mass grows, the body is also recomposed due to increased fat burning, which the athlete’s body a carved (cutting) look.  
•  Increase in bone mineral density 
•  Prostate protection. A feature and positive property of S4 compared to other SARMs is that a partial agonist of androgen receptors in prostate cells. Thus, it binds to them without activating them, but blocking them from attaching   DHT. Thus, there is no stimulation of prostate growth. In a sense, S4 protects the prostate from the androgenic effects of DHT when used in combination with DHT anabolic steroids. 

Testosterone suppression 

Andarine, like any other SARM, suppresses the natural production of testosterone. S4 is more inhibitory than Ostarine but much less than other SARMs such as LGD4033 or RAD140. Many users have noticed that S4 suppresses testosterone much less significantly than most other SARMs. To maximize the drop in testosterone levels in the blood – you should take SERMs (clomiphene, tamoxifen) or testosterone / gonadotropin during the cycle of Ligandrol so that your testosterone level in the blood is sufficient. 

Effect on the liver

There are no reports of Andarine causing an increase in liver enzymes, however be careful with S4 dosage as it may cause other side effects at higher dosages. 

Change in lipid profile 

Although to a lesser extent than anabolic steroids, all SARMs can affect cholesterol levels to some extent. Most often, they decrease HDL (good cholesterol) levels and increase LDL (bad cholesterol) levels. During your S4 cycle, you will need to take these blood tests to keep your cholesterol levels under control. 

Vision change 

Depending on the individual, after a certain dosage, S4 may cause temporary visual impairment, such as the appearance of a yellowish tint, impaired night vision and the ability to adapt to changes in brightness, as well as blurred vision. This side effect disappears almost immediately after the drug is discontinued. 

Take S4 starting from the minimum dosages and if you get this negative effect, reduce the dosage to the one at which this effect will not be. 

Half-life

• 4-6 hours 

Dosage 

• Minimum working dosage (beginner) 20 mg
• Average dosage 25-75 mg
• Maximum recommended 100 mg
• Women 10-20 mg