What is Testosterone Enanthate?
Testosterone stands as the primary sexual hormone within the human body, holding a pivotal role in the maturation of male reproductive organs such as the testes and prostate, while also exerting influence on both male and female physiology. Additionally, it serves as the catalyst for secondary sexual traits in males, heralding enhancements in muscle and bone density, along with the growth of bodily hair. Beyond this, the contribution of testosterone extends to holistic health and a sense of well-being, playing a key part in thwarting osteoporosis across genders. Diminished test levels can give rise to challenges like frailty and bone degeneration in men. With pronounced anabolic properties, testosterone acts as a potent stimulant for muscle growth, expediting protein synthesis, propelling recovery rates, and augmenting the supply of glycogen to muscular tissues. This hormone presides over an array of bodily processes, rendering it the preeminent and unceasingly necessary hormone. This characteristic underscores the utilization of testosterone medications by both elderly individuals contending with age-related hypogonadism and athletes embarking on steroid regimens as a foundational component.
How it works?
Testosterone, a key hormone in humans, binds to androgen receptors and serves as a precursor to another biologically active androgen, dihydrotestosterone (DHT).
DHT is formed when testosterone encounters the enzyme 5α-reductase and has a binding affinity for androgen receptors that is five times greater than test. When these hormones interact with receptors, the receptor structure changes, sending a signal to the cell nucleus.
This interaction leads to androgenic effects, which are realized through changes in the activity of specific DNA genes. Testosterone can also be converted to estrogen under the influence of the enzyme aromatase, a process known as aromatization. It is predominantly estrogens, rather than testosterone, that activate the feedback mechanism through the hypothalamus-pituitary-testes axis, suppressing the secretion of endogenous test when exogenous drugs are administered.
More than 40% of man after 35 years old has the lack of testosterone according to the blood tests, so testosterone deficiency is the main reason to buy testosterone enanthate online
What are other names and how do they differ?
This hormone itself permanently produces in men’s testicles and its molecule has a 2-4 hours period of life.
Therefore, for ease of use, so as not to make injections every 2 hours, an ether tail was chemically attached to the test molecule, which slows down the release of free testosterone into the blood.
Ethers come in different "lengths":
- Testosterone propionate (Propios, Testoviron) has a 0.8 days half-life
- Testosterone enanthate (Testen, Delatestryl) has 4.5 days half-life
- Testosterone cypionate (Cypilos, Depo-Testosterone) has a 5 days half-life
- Testosterone undecanoate (Andriolos, Aveed, Nebido, Jatenzo) has a 21-34 days half-life
They are all the same hormone but the dynamics of release are different.
Benefits of for the body and health
Testosterone is included in the World Health Organization's list of essential medicines, which are the most important medications needed in a basic health system, so the opinion that its only anabolic steroid for making muscles bigger and stronger is wrong, it’s a vital hormonal drug. Testosterone is used as a medication for the treatment of gender dysphoria, male hypogonadism and certain types of breast cancer.
Since testosterone levels decrease as men age, to maintain health and quality of life, it is necessary to add hormone replacement therapy (HRT) or testosterone replacement therapy (TRT). HRT maintains serum testosterone levels in the normal range. Decline of testosterone production with age has led to interest in androgen replacement therapy.
Mood, spatial ability, attention, memory, and other key cognitive functions affected by testosterone in humans. Preliminary evidence suggests that low testosterone levels is a risk factor for cognitive decline and possibly for dementia of the Alzheimer's type.
In both sexes testosterone is involved in health and well-being and in the prevention of osteoporosis. Insufficient levels of this hormone in men may lead to abnormalities including frailty and bone loss. Also, testosterone treatment is beneficial in adult men with age-related low levels of testosterone who have sexual dysfunction.
- Beginner: 250 mg week
- The average dosage: 300-750 mg week
- High dosage: 750+ mg week
Half-life for test enanthate is 4.5 days
Testosterone Enanthate side effects
- Increased blood pressure
- Increased sexual behaviour
- Hemoconcentration (blood clotting)
- Possibility of blood clots in arterial and venous vessels
- Water accumulation (edema)
- Aggression, agitation, irritability
- Alopecia (baldness of the scalp)
- Acne (acne)
- Insomnia (rare)
Testosterone, the primary male androgen, can cause androgenic side effects like oily skin, acne, and body/facial hair growth at elevated levels. It may accelerate balding in genetically predisposed men. Nandrolone decanoate, a less androgenic steroid, may be a better option for hair loss concerns. Women risk virilizing effects like voice deepening and facial hair growth.
In tissues like the skin and scalp, testosterone's androgenicity depends on its conversion to dihydrotestosterone (DHT) by the 5-alpha reductase enzyme. 5-alpha reductase inhibitors like finasteride can reduce androgenic effects by blocking this conversion. However, complete separation of testosterone's anabolic and androgenic effects is not possible, even with total 5-alpha reductase inhibition.
Testosterone easily converts to estrogen estradiol in the body, a process managed by the aromatase enzyme. Elevated estrogen can lead to the following side effects: water retention, fat gain, gynecomastia, mood swings.
Testosterone is moderately estrogenic, so an anti-estrogen like clomiphene or tamoxifen may be needed to counter these effects if already appeared.
Alternatively, aromatase inhibitors like (anastrozole) can efficiently control estrogen by blocking its synthesis.
Estrogenic side effects increase with higher test doses, making concurrent use of anti-estrogens or aromatase inhibitors more likely. Since high doses cause water retention and reduced muscle definition, testosterone is not ideal for dieting or cutting but is better suited for bulking, where added water supports strength and muscle growth, creating a more anabolic environment.
Anabolic/androgenic steroids can negatively affect cholesterol levels, decreasing HDL (good) cholesterol and increasing LDL (bad) cholesterol, potentially increasing the risk of arteriosclerosis. These effects depend on factors like dose, administration route, steroid type, and resistance to liver metabolism. Steroids can also adversely affect blood pressure, triglycerides, endothelial relaxation, and support left ventricular hypertrophy, potentially increasing cardiovascular disease and heart attack risk.
Testosterone has less impact on cardiovascular risk factors than synthetic steroids, partly due to liver metabolism, reducing its effect on cholesterol management. The aromatization of the hormone to estradiol also mitigates the negative effects of androgens on lipids. However, studies show that aromatase inhibitors can significantly decrease HDL cholesterol when used with testosterone, so their addition to test therapy should be carefully considered.
Risks of the higher dosage
With an excess dosage of testosterone enanthate, positive side effects increase slightly, at the same time, as the frequency of negative side effects skyrockets: first of all its androgenic and estrogenic side effects, then comes cardiovascular side effects.
Everybody is different so it’s impossible to predict your personal reaction.
All negative side effects are listed in a chapter above.
How to use it for men?
There are two main spheres of using testosterone for men:
Testosterone for seniors
For men over 35 who report issues with well-being, it's often suggested that they have their blood testosterone levels checked. If their levels are found to be below 12 nmol/l, they may be advised to consider hormone replacement therapy (HRT). This approach has several advantages. Body composition tends to improve, with an increase in muscle mass and a decrease in fat. Sexual function may experience a revival, and there may even be a rejuvenating effect. Overall, the body benefits by reversing the negative impacts it experienced during the period of androgen deficiency.
However, medical supervision is crucial during HRT. Regular monitoring of lipid profiles, general clinical blood parameters, and estradiol and prolactin levels is necessary.
It's crucial to bear in mind that hormonal replacement therapy (HRT) can potentially suppress the production of natural gonadotropins to almost negligible levels. As a result, individuals aspiring to conceive might find it necessary to pursue specialized treatments involving gonadotropins.
Precisely calibrating the suitable measure of testosterone therapy mandates a comprehensive discussion with a medical professional. Dosage determination takes into account various factors including baseline and prevailing testosterone levels, body weight, percentage of body fat, sex hormone-binding globulin (SHBG) concentrations, and the conversion of testosterone to estrogen through aromatization.
It's worth noting that the recommended dosages for replacement therapy, typically ranging from 50-200 mg per week, are much lower than those used by athletes.
Testosterone in sports
Testosterone's primary benefit is an increase in muscle mass and strength. Alongside its anabolic effect, the drug also has a potent androgenic impact. Androgens function by entering a cell and interacting with the AR protein. This interaction prompts the AR protein to alter its shape and activate. Although this change is subtle, its impact is significant, enabling the AR to enter the cell nucleus and attach to the DNA, a process known as DNA binding.
The swift weight gain associated with test hormone is often due to substantial water retention, resulting from sodium retention and estrogenic effects. As such, testosterone is frequently used to address joint issues, including pain and crunching in the shoulders and knees, although nandrolone and growth hormone are generally more preferred for this purpose. Testosterone stimulates regenerative processes within the body, enhances overall tone and workout motivation, and prevents overtraining. It also increases blood oxygen capacity and nitric oxide production, leading to an impressive pump during exercise.
In sports, the suggested dosage is typically 250-500 mg per week. As an athlete's body weight increases, the dosage is often adjusted upward. Testosterone cycles usually last 8-10 weeks, followed by post-cycle therapy 2-3 weeks later. However, it is frequently used for more extended periods. In high-level professional athletes, the maximum dosage is 2000 mg per week. Beyond this, increasing the dosage serves no purpose other than escalating side effects.
To prevent estrogenic side effects due to the aromatization process, it's crucial to undergo tests and consider using aromatase inhibitors. It's best to check estradiol levels before and during the use of aromatase inhibitors to monitor their effectiveness and determine the appropriate dosage. We strongly advise to entrust dosage selection to professionals. However, the information provided here is for reference purposes.
How to use it for women? Precautions about pregnancy and breastfeeding
Testosterone Enanthate is seldom used in women for clinical purposes, typically reserved for inducing masculinization in female-to-male transsexuals. It is not recommended for women seeking to enhance their physique or performance because of its strong androgenic properties, potential for virilizing side effects, and slow-acting nature, making blood levels hard to control.
Testosterone enanthate is not recommended for use by pregnant or breastfeeding women. It can cause masculinization of a female fetus and may transfer through breast milk, potentially affecting a nursing infant. It can also cause male-like changes in women.
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Where to buy Testosterone Enanthate in Europe?
If you want to purchase real Testosterone Enanthate online you should check before ordering because it’s important to be sure of the purity and quality of the product they sell. Independent labs can make the tests and give a report of Testosterone Enanthate content in a tab.
So in Europe, you can buy real lab-tested Testosterone Enanthate with proven quality from Driada Medical shop with 100% delivery rate.
1. How fast does testosterone enanthate work?
After the injection, it begins to resease to the bloodstream immediately, however, to achieve effects, the concentration of the hormone in the blood must be maintained for some time so people claim that the effect of the injection is felt on the second third day.
2. How do you feel on testosterone enanthate?
If you have a reduced level of this hormone , the use of testosterone enanthate will return the level of this hormone to a normal value, it will give strength to your bones, put your libido, mood and immunity in order. There are more than 140 processes in which testosterone plays a key role, so hormone replacement therapy improves health and prolongs life, significantly improving its quality.
Elevated testosterone level can lead to both physical and emotional changes. Physically, it can increase muscle mass, decrease body fat, and cause oily skin and acne. Men may also experience increased libido, enlarged breasts, and a higher risk of heart attack and stroke. Emotionally, excessive testosterone can cause mood swings, irritability, aggression, and risky behavior. It can also affect sleep patterns, leading to insomnia and other sleep disorders. In the long run, excessive testosterone can lower natural testosterone production.
3. Is enanthate better than cypionate?
Testosterone cypionate and testosterone enanthate are both forms of this hormone used in hormone replacement therapy, and they are very similar in their structure and function. The primary difference between the two is their ester length, which affects the rate at which the testosterone is released into the body. This impacts the dosing frequency of the two compounds.
Cypionate has a slightly longer ester chain than enanthate, meaning that it will stay in the body for a longer period of time. Testosterone cypionate is more commonly used in the United States, while testosterone enanthate is more popular in Europe and other parts of the world.
4. How much test enanthate should I inject to build muscle?
Testosterone enanthate is often used during bulking phases of training, where the added water retention is less of a concern, and the focus is on gaining raw mass rather than muscle definition. While some use this drug in cutting cycles, it's usually in smaller doses of 125-250 mg every 7-10 days and/or alongside an aromatase inhibitor to manage estrogen levels. As a potent anabolic substance, testosterone enanthate can be used effectively on its own.
However, some users prefer to stack it with other anabolic/androgenic steroids, like boldenone undecylenate, methenolone enanthate, or nandrolone decanoate, at an additional 200-400 mg per week for a more powerful effect without significant liver toxicity. Testosterone is highly adaptable and can be combined with various anabolic/androgenic steroids to achieve the desired outcome.
Some bodybuilders have been known to use very high dosages of this drug, up to 1,000 mg per week or more, although this is generally not recommended. At dosages above 750 mg per week, the weight gain is likely to be more from water retention than new muscle tissue. Such "megadosing" is inefficient and possibly harmful, particularly considering the typically high cost of testosterone enanthate, and is not usually justified outside of intense bodybuilding programs.