Being synthesized in the liver mainly from amino acids such as L-cysteine, L-glutamic acid and glycine, glutathione is considered an interchangeable amino acid, although it is believed that only about 100 mg of this amino acid can be found in foods that the average person eats (usually in protein-rich foods such as meat of various animals), more less of this amino acid is absorbed by the human body and an even smaller amount of it is directly consumed by the body. It has been proven that stress caused by training reduces glutathione levels in the body and negatively affects endurance performance, immunity and recovery rates, and therefore the use of special supplements that regulate glutathione levels has a beneficial effect on an athlete's physical fitness.
TAD-600 is a pharmaceutical glutathione, a powerful antioxidant found naturally in the body. It is used in medical treatments to combat oxidative stress and detoxify the body. Glutathione plays a critical role in protecting cells from damage by free radicals and toxins.
Glutathione is a naturally occurring, very powerful antioxidant. When taking liver supplements like NAC, it works by increasing your body's glutathione levels, which protects your organs from free radicals and toxins that can damage them. Taking glutathione directly provides a much more effective dose. Glutathione is produced by the liver and is also found in fruits, vegetables, and meats.
People take glutathione for treating cataracts and glaucoma, preventing aging, treating or preventing alcoholism, asthma, cancer, heart diseases (atherosclerosis and high cholesterol), hepatitis, liver diseases, diseases that weaken the immune system (including AIDS and chronic fatigue syndrome), memory loss, Alzheimer's disease, osteoarthritis, and Parkinson's disease. Glutathione is also used for maintaining the immune system and fighting metal and drug poisoning.
Glutathione is inhaled for treating lung diseases, including idiopathic pulmonary fibrosis, cystic fibrosis, and lung disease in people with HIV. Healthcare providers administer glutathione via intramuscular injections to prevent the toxic side effects of cancer treatment (chemotherapy) and for treating male infertility. Healthcare providers also give glutathione intravenously to prevent anemia in kidney patients undergoing hemodialysis, prevent kidney problems after heart bypass surgery, treat Parkinson's disease, improve blood flow and decrease clotting in individuals with atherosclerosis, treat diabetes, and prevent the toxic side effects of chemotherapy.
Mechanism of Action
Glutathione works by neutralizing free radicals, thus preventing cellular damage. It also supports the detoxification processes in the liver, aids in the metabolism of fats and proteins, and enhances the immune system by regenerating other antioxidants like vitamins C and E. Glutathione is a linear tripeptide with a sulfhydryl group, which includes L-glutamine, L-cysteine and glycine. It plays an important function in protecting the body's cells, being a strong antioxidant. In the human body, a lack of glutathione leads to many diseases, such as Parkinson's disease, tyrosinemia type I, alcohol poisoning and others. In vivo and in vitro experiments have shown that a lack of glutathione can lead to damage to mitochondria and cell death caused by an increase in the number of toxic oxygen species, leading to an increase in the number of free radicals. The neutralization system with the participation of glutathione plays a unique role in the formation of the body's resistance to a variety of influences and is the most important protective mechanism of the cell.
Glutathione binds a huge number of lipophilic compounds (physical neutralization), preventing their introduction into the lipid layer of membranes and disruption of cell functions. Thus, glutathione improves the stability of the cell membrane, protects the membrane of liver cells, increases the activity of enzymes and the liver and promotes detoxification and regenerative activity of the liver by destroying free radicals.
Glutathione and COVID-19. Adding glutathione to the treatment of severe COVID-19 can reduce life-threatening complications by restoring the effective functioning of the body's defense systems, leading to faster recovery and a milder course of the disease.
Usetoimprovesportsachievements
Glutathioneis a verypopularsupplementused by athletesbecauseithasmanybeneficialpropertiesand is consumedinresponsetophysicalexertion.It is considered the “mainantioxidant”andis the maindetoxificationand anti-inflammatoryagentineverycell of yourbody.It is especiallyusefulin the world of athleticsandothersportsdue to itsability to preventandeliminatetissuedamage,unnecessaryinflammation,infections,muscleweaknessandoverwork.
As anantioxidant,glutathionehelpsimproveathleticperformance by protectingcellsfromdamagecaused by the formation of freeradicalsduringexercise,especiallywhentheirlevelsexceed the body's ability to defendagainstthem. For example, an athletereturnstotrainingandpreparingforcompetitionsafter a longbreak,begins a newanddifficulttrainingcycle,or an athlete is exposed to suchstressesasbeingon high ground(for example,inmountains),in a placewheresmogaccumulates,orinveryhotorcoldclimaticconditions.
