Unlocking the Power of Supplements and Steroids for Muscle Growth

In the pursuit of achieving remarkable gains in muscle mass, many individuals turn to supplements and steroids. While traditional wisdom might suggest that mega doses of testosterone are the key, recent research from the University of California suggests a different approach. You can achieve substantial results with a more moderate approach, combining oxandrolone and testosterone enanthate for just 8 weeks.

Back in 1999, this groundbreaking study was published in the prestigious Journal of the American Medical Association (JAMA). The researchers were responding to previous studies that had exposed HIV-infected men to heavy doses of steroids, such as 600 mg of nandrolone decanoate per week, alongside weight training. However, this new study challenged the need for such high doses.

The research team conducted a trial involving 22 HIV patients, administering 20 mg of oxandrolone daily and a weekly 100 mg injection of testosterone enanthate. The course was relatively short, lasting only 8 weeks, but the results were astonishing.

During this period, the participants engaged in 1-hour weight training sessions three times a week, under the guidance of a trainer. Their training regimen consisted of 6 fundamental exercises for the main upper body muscle groups and 3 exercises for the lower body. They used weights that were equivalent to 80 percent of the weight they could lift for a single repetition (1RM).

Eleven of the participants received a weekly injection of 100 mg of testosterone enanthate alongside a placebo. The remaining eleven individuals were administered 20 mg of oxandrolone daily.

The results were nothing short of impressive. The oxandrolone group gained nearly 8 kg of fat-free mass in just 8 weeks. Furthermore, the oxandrolone group experienced accelerated strength gains compared to the placebo group. The bench press and leg press maximal weight gains were 20 and 30 kg, respectively, for the oxandrolone group, whereas the placebo group saw increases of 10 and 20 kg.

Additionally, the oxandrolone group shed a few ounces more fat compared to the placebo group. This study reveals that achieving an 8 kg gain in fat-free mass doesn't require a 20-week regimen of 600 mg doses. Instead, these remarkable results can be accomplished with more moderate doses.

However, it's important to note that even this mild oxandrolone-testosterone course was not entirely without side effects. One participant from the oxandrolone group had to discontinue due to unusual liver enzyme levels. Blood analysis also indicated that the addition of oxandrolone to the relatively modest testosterone course further suppressed the body's natural testosterone production. Additionally, the oxandrolone group exhibited decreased LH and FSH hormone production, which stimulate the testes to produce testosterone. It's worth noting that some participants were taking retroviral medications, but these did not impact the effects of the steroids.

In conclusion, this study demonstrates that the combination of resistance exercise with a moderately supraphysiologic androgen regimen, including oxandrolone, can lead to significant increases in lean tissue and muscle strength. This approach offers promising results for individuals, particularly those facing unique challenges such as HIV infection. The use of protease inhibitor therapy did not affect the lean tissue response.