Phosphodiesterase-5 inhibitors, such as sildenafil, increase the level of cyclic guanosine monophosphate, which leads to the relaxation of the smooth muscles of the body and the erection of the penis. This helps to achieve a good erection more quickly and increases the possibility of repeated sexual intercourse. But, in addition to this, this type of drug has other properties.
Studies have shown that in addition to this effect, sildenafil has a direct effect on testosterone levels, increasing it, most likely due to a direct effect on the testicles. In addition to testosterone itself, dihydrotestosterone estradiol levels also increased. https://pubmed.ncbi.nlm.nih.gov/24106072/
This study was conducted on men with reduced testosterone levels, which gives us the prerequisites for using sildenafil, for example, during a break from testosterone and other anabolic steroids to increase overall testosterone levels. Tadalafil also showed itself well, which significantly raised testosterone with a daily intake of 5 mg for 3 months. https://pubmed.ncbi.nlm.nih.gov/28295481/
Thus, if these drugs are well tolerated, you can easily include them during your PCT and solve several problems at the same time.
Firstly, you will be able to improve your erection if you encounter this problem during your PCT, and secondly, you will help increase testosterone levels in conjunction with the work of drugs such as SERMs.
And, thirdly, phosphodiesterase-5 inhibitors are known to have a beneficial effect on the prostate, as a means of preventing its hyperplasia.
Given that tadalafil has no significant side effects for most users, this drug can greatly add to PCT in the long term. We suggest using low dosages such as 5-10 mg/day.
Sildenafil will be somewhat less successful for this use as its effect lasts about 6 hours (as opposed to 24-36 hours for tadalafil) and often has side effects such as nasal congestion and redness of the face.
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