Enhanced Hormonal Response from Training: The Benefits of Phosphatidylserine

Recent studies reveal that Phosphatidylserine, a key supplement, positively influences the body's hormone levels post-exercise. An experiment involving healthy males, where each was given 600 mg of Phosphatidylserine daily for a ten-day period, showed a significant increase in testosterone and a decrease in cortisol levels after a short, intense workout session.

This promising outcome emerged from research conducted at the University of Mississippi. The study involved ten participants who underwent exercise sessions including cycling and varying intensity workouts. These sessions tested the impact of Phosphatidylserine on key hormones like cortisol, testosterone, lactate, and growth hormone.

Found in cell membranes, Phosphatidylserine is known for enhancing receptor function and stress resistance. Its exact mechanism remains a subject of study, but it's known to reduce cortisol post-exercise and during stress. This study aimed to ascertain if this supplement could yield a better hormonal response, essential for progress in training, as it is believed that a balance of less cortisol and more testosterone is conducive to better muscle development.

The results were encouraging. Participants who took the supplement showed a noticeable reduction in cortisol production and an increase in testosterone levels. These findings are particularly significant in sports science, where the cortisol-testosterone ratio is a key indicator of the body's muscle-building capacity. Experts often suggest evening workouts for optimal hormonal balance, and the study's findings support this, showing improved hormonal ratios with supplement intake.

In terms of lactate and growth hormone levels, the supplement's impact was less pronounced. However, the overall results indicate a positive shift in hormonal balance favoring muscle development and recovery post-exercise.

While Phosphatidylserine is present in lecithin, its concentration is low, and a higher dosage is necessary to achieve the levels used in the study. This points to the effectiveness of supplement forms in achieving the desired hormonal response.

Abstract and Background

The study aimed to assess the impact of Phosphatidylserine on key exercise-related hormones. Previous research hinted at its ability to lower cortisol levels, with varying results based on dosage. This study focused on a moderate dose of 600 mg per day and its effects on cortisol, lactate, growth hormone, and testosterone levels in healthy males.

Participants underwent a double-blind, placebo-controlled, crossover design study, where they ingested 600 mg of Phosphatidylserine or a placebo for ten days. Blood samples were taken at different stages of a moderate-intensity exercise regime to measure hormone levels.

The findings were clear: Phosphatidylserine effectively reduced cortisol levels and increased the testosterone-to-cortisol ratio, marking it as a beneficial supplement for athletes facing exercise-induced stress. These results support the use of Phosphatidylserine in promoting a healthy hormonal balance, crucial for avoiding overtraining and maintaining peak physical condition.

Discussion and Conclusion

The study's findings suggest that short-term supplementation of Phosphatidylserine can significantly alter the body's hormonal response to stress from exercise. The observed lower cortisol levels and higher testosterone concentrations point to an improved physiological state for athletes.

The study adds to the growing body of evidence suggesting the potential of Phosphatidylserine in enhancing athletic performance, aiding in recovery, and maintaining a healthy hormonal balance. Its impact on the testosterone-to-cortisol ratio is particularly noteworthy, as this ratio is a critical marker of an athlete's training state and overall physical health.

In conclusion, supplementing with 600 mg of Phosphatidylserine daily for ten days can be a strategic approach to mitigating exercise-induced stress and promoting an optimal hormonal environment for athletes and fitness enthusiasts. The study paves the way for further exploration of Phosphatidylserine's role in sports nutrition and its potential benefits in broader health contexts, such as managing stress-related conditions and enhancing overall well-being.