MK-2866 (Ostarine)

Shortly about MK2866

•  The most selective and therefore the safest SARM in terms of side effects. Great for women and those who do not want to receive any side effects. 
•  Increases lean muscle mass and strength, but is inferior to other SARMs when it comes to safety. An ideal choice for those who are not in a hurry and are ready to improve their results gradually, but without side effects. 
•  Reduces body fat
•  SARMs have the most gentle effect on their own testosterone, so recovery after a cycle is much easier and faster. 
•  Like other SARMs it affects the lipid profile and can increase liver enzymes. 
• The most unexplored SARM science at the moment 

What is Ostarine?

Ostarine is one of the mildest, safest and most researched SARMs, but even though it is considered the mildest, it can give excellent results. It is designed to selectively affect the androgen receptors in our body. It is most selective on androgen receptors, which means that it reduces unwanted side effects such as an enlarged prostate or significant hair loss. While side effects are still possible with this compound, they are very few and very mild. 

Researches 

Ostarine also referred to as MK 2866, was developed by GTx Inc.in 1997 for the treatment of diseases associated with muscle wasting and osteoporosis. In 2007, Ostarin was already in Phase 2 clinical trials. There were many human trials of Ostarin in 2011. One study that focused on older men found that Ostarine resulted in a significant increase in lean body mass. In 2016, Ostarin failed a phase 3 clinical trial for the treatment of muscle wasting disorders in people with lung cancer. These trials failed because people with lung cancer were physically too weak to use the substance. Ostarine is still considered to be in development, successfully passing numerous trials, to one day be recognized as an official treatment for muscle wasting diseases. 

Effects 

• Muscle gain with Ostarin is not very over the top, but it is definitely the safest way to increase muscle mass given the very mild nature of this currently most studied SARM.
• Increase in strength indicators. The increase in strength with Ostarine are also quite noticeable. Improvements should be clearly noticeable, especially in users who have never used any anabolic agents before.
• Increased bone mineral density. Decreased levels of sex hormones with age also increase the likelihood of developing osteoporosis, a bone disease in which bones become brittle and weak. With the help of Ostarin, the likelihood of bone fractures is reduced in people and the rate of recovery is increased by increasing muscle mass. Ostarine has the ability to stop bone diseases because its action is similar to that of testosterone. 
• Some reduction in body fat.

Testosterone suppression 

As we have already told about SARMs – MK2866 will suppress your natural testosterone production, however the suppression from this compound, provided it is genuine and high quality, will bery mild and barely noticeable. Its mild effect on the production of its own testosterone is its main advantage. Using moderate doses will give you the opportunity to have normal testosterone levels during the cycle and easily restore it after if it was low. While this approach is good for the intended purpose, you should still have ongoing overall testosterone lab tests to monitor your levels and see if Ostarine is negatively impacting your levels. To avoid drop in blood testosterone as much as possible – you should take SERMs (clomiphene, tamoxifen) or testosterone / gonadotropin during the cycle of Ligandrol so that your blood testosterone level is sufficient. 

Effect of the liver

SARMs, although less significant than oral anabolic steroids, do have some effect on the liver. Ostarine may increase the liver enzymes ALT and AST. Supplements such as NAC 600-1200 mg, TUDCA – 500 mg and ALA – 500 mg taken together or separately provide protection against this side effect. 

Change in lipid profile 

Although to a lesser extent than anabolic steroids, all SARMs can affect cholesterol levels to some extent. Most often, they decrease HDL (good cholesterol) levels and increase LDL (bad cholesterol) levels. During your Ostarine cycle, you will need to take these blood tests to keep your cholesterol levels under control. 

Hal-life

• 24 hours 

Dosages 

• Minimum working dosage (beginner) 10 mg
• Average dosage 20-50 mg
• Maximum recommended – 100 mg
• Women 5-10 mg